| 英文品名 |
muromononab-CD3 |
| 名称来源 |
p-INNList-59,1988;r-INNList-29,1989; |
| 别 名 |
Muromonab-CD3，Anti-CD3 Mab, OKT-3 antibody, Orthoclone OKT-3 |
| 化学表述 |
A biochemically purified lgG2a immunoglobulin consisting of a heavy chain of approx. 50,000 daltons and a light chain of approx. 25,000 daltons. It is manufactured by a process involving the fusion of mouse myeloma cells to lymphocytes from immunized animals to produce a hybridoma which secretes antigen-specific antibodies to the T3 antigen of human T-lymphocytes. |
| CA登记号 |
140608-64-6 |
| 品种类别 |
抗肿瘤及免疫调节药>选择性免疫抑制药; |
| ATC 编码 |
L04AA02; |
| 参考文献 |
MI(6332)；EP 33578；Lancet., 1987, 1, 237；Br.Med.J., 1987, 295, 1099；Br.Med.J., 1987, 295, 1486 |
| 简介 |
1986年上市（强生，美国）。一种单克隆抗T细胞抗体，用于肾、心脏和肝移植的排异和使供体骨髓的T细胞在移植前失活。 |
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