配方类型: |
DRUGS |
配方说明: |
Rapidly Disintegrating Coatings for Pills (Colored) |
配方组成: |
Dry Lacquer Substance Content/5% Lacquer Dispersio Hydroxypropyl Methylcellulose/10 Talc/Magnesium Stearate/159 Polyethylene Glycol 6000/30 Antifoam Agent/1 Titanium Dioxide/Color Pigment/100 "Eudragit" E 30 D/333 Water/700 Water/667 Solids Content/20% |
配制方法: |
To produce the pigment suspension, water is measured out and the solids are added and stirred in. Hydroxypropyl methylcellulose (e.g., "Methocel" E5) is dissolved in water beforehand to produce a 10% solution and is then added, followed by the polyethylene glycol 6000 as a 33% aqueous solution. Next the whole pigment suspension is finely dispersed, using a suitable dispersion system (toothed colloid mills, corundum disc mills, ball mills), and is poured into the diluted "Eudragit" E 30 d dispersion, but only immediately prior to use. The mixture should be processed within one to two days. |
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