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    配方类型: DRUGS
    配方说明: Tablets (Griseofulvin, 250 mg)
    配方组成: "Cab-O-Sil" M-7/1.50
    Starch Paste (30% W/V)/1.67
    "Veegum" F/8.33
    "Emdex"/10.00
    "Avicel" PH 101/19.16
    Lactose/16.67
    Griseofulvin (micronized)/41.67
    Stearic Acid/1.00
    配制方法: Prepare a wet granulation of griseofulvin. Mix the griseofulvin, lactose, and starch paste and pass through a 14-mesh sieve. Dry the granules in a 60 C oven for 6 h. Collect granules passing through a 20-mesh sieve. Combine griseofulvin granules, "Veegum" F, "Emdex," and "Avicel" PH 101 and mix for 15 min. Add the stearic acid and "Cab-O-Sil" to the mixture and blend for an additional 10 min. Compress.
    Mean Tablet Wt. (n=20)---597 mg Mean hardness---7 kg Friability---0.27% Disintegration Time (Purified water)---3 min

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