中文名称：阿那曲唑
  • α,α,α'α'-四甲基-5-(1H-1,2,4-三唑-1-基甲基)-1,3-苯二乙腈; α,α,α',α'-四甲基-5-(1-H-1,2,4-三唑-1-甲基)-1,3-二乙氰苯; 四甲基-5-(1H-1,2,4-三唑-1-基甲基)-1,3-苯二乙腈
  • Anastrozole
  • Tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-benzenediacetionitrile; ICI-D-1033; Arimidex; 1-[3,5-DI-(1-METHYL-1-CYANO)-ETHYL]-BENZYL-1,2,4-TRIAZOLE; ANASTRAZOLE; tetramethyl-5-(1h-1,2,4-triazol-1ylmethyl) 1,3-benzenediacetionitrile; ZD-1033; 1,3-benzenediacetonitrile,alpha,alpha,alpha',alpha'-tetramethyl-5-(1h-1,2,4-triazol-1-ylmethyl)-; Anastrozol; Anatrozole; ZD-1033, ICI-D-1033, Arimidex; 2-[3-(2-Cyano-2-propyl)-5-(1,2,4-triazol-1-ylmethyl)phenyl]-2-methylpropiononitrile; 1,3-benzenediacetonitrile, alpha,alpha,alpha',alpha'-tetramethyl- 5-(1h-1,2,4-triazol-1-ylmethyl)- zd; 1,3-Benzenediacetonitrile,a,a,a',a'-tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl); 2,2'-[5-(1H-1,2,4-triazol-1-ylmethyl)benzene-1,3-diyl]bis(2-methylpropanenitrile)
  • 120511-73-1
  • C17H19N5
  • 293.37
  • InChI=1S/C17H19N5/c1-16(2,9-18)14-5-13(8-22-12-20-11-21-22)6-15(7-14)17(3,4)10-19/h5-7,11-12H,8H2,1-4H3
  • 阿那曲唑 120511-73-1
  • 81-82℃

  • 白色或类白色结晶性粉末。

    熔点 81-82°C

  • 强效的选择性的三唑类芳香酶抑制剂，它能抑制细胞色素P-450所依赖的芳香酶从而阻断雌激素的生物合成，而雌激素为刺激乳腺癌细胞生长的主要因素。治疗乳腺癌，特别适用于那些用激素辅助治疗之后复发的经绝期后妇女的晚期乳癌。