中文名称：达若鲁胺
- 达洛鲁胺; 达罗他胺; ODM-201; N-[(1S)-2-[3-(3-氯-4-氰基苯基)-1H-吡唑-1-基]-1-甲基乙基]-5-(1-羟基乙基)-1H-吡唑-3-甲酰胺;
- Darolutamide
- Darolutamide (ODM-201); ODM-201; N-{(2S)-1-[3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl]propan-2-yl}-5-[(1RS)-1-hydroxyethyl]-1H-pyrazole-3-carboxamide;
- 1297538-32-9
- 398.8462
- 1.41±0.1 g/cm3(Predicted)
- 719.5±60.0 °C(Predicted)
- DMSO: ≥ 44 mg/mL
- 生物活性 Darolutamide (ODM-201, BAY-1841788)是一种新型androgen receptor (AR)拮抗剂，能够阻断AR核转运，其Ki为f 11 nM。Phase 3
- 5-(1-Hydroxyethyl)-1H-pyrazole-3-carboxylic、acid、2-氯-4-(1H-吡唑-3-基)苯甲腈、ORM-15341、4-溴-2-氯苯腈
- 5-(1-Hydroxyethyl)-1H-pyrazole-3-carboxylic、acid、2-氯-4-(1H-吡唑-3-基)苯甲腈、ORM-15341、4-溴-2-氯苯腈