中文名称:氟尿苷
- 氟苷; 氟脲脱氧核苷; 5-氟去氧尿苷; 2'-脱氧-5-氟尿嘧啶核苷; 2'-脱氧-5-氟尿苷; 5-氟-2'-脱氧尿苷; 5-氟-2'-脱氧脲核苷; 氟脲苷; 5-氟-2-脱氧脲核苷
- (+)-5-Fluoro-2'-deoxyuridine
- Deoxyfluorouridine; 5-Fluoro-2-deoxyuridine; FUDR; 5-Fluoro-2?Deoxy Uridine; 2-Deoxy-5-fluorouridine; Floxuridine; 5-FUDR; (+)-5-Fluoro-2?deoxyuridine; 1-(2-deoxypentofuranosyl)-5-fluoropyrimidine-2,4(1H,3H)-dione; 1-(2-deoxy-D-threo-pentofuranosyl)-5-fluoropyrimidine-2,4(1H,3H)-dione; 5-Fluoro-2'-deoxyuridine; (+)-5-Fluorodeoxyuridine
- 50-91-9
- 200-072-5
- C9H11FN2O5
- 246.1924
- InChI=1/C9H11FN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16)/t5-,6-,7?/m1/s1
- 1.64g/cm3
- 148-153℃
- soluble
- 熔点 148 °C(lit.)
沸点 150 °C
比旋光度 35.9 o (c=1, water)
储存条件 2-8°C
水溶解性 soluble
Merck 14,4112
BRN 2645818
- 抗肿瘤药。适用于治疗肝癌、胃肠道癌、乳腺癌及头颈部癌。可有骨髓抑制。胃肠道反应和皮肤局部反应等副作用与氟尿嘧啶相似。亦有碱性磷酸酶、血清转氨酶、血清胆红质和乳酸脱氢酶等增高现象。
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Xn:Harmful;
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R22:;
R36/37/38:;
R68:;
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S26:;
S36/37/39:;
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