中文名称:卡麦角林
  • 6-烯丙基-N-[3-(二甲基氨基)丙基]-N-(乙基氨基甲酰基)麦角林-8-甲酰胺; (8Β)-N-[3+(二甲氨基)丙基]-N-[(乙氨基)羧基]-6-(2-丙烯基)麦角林-8-羧酰胺
  • Cabergoline
  • 6-allyl-n-[3-(dimethylamino)propyl]-n-(ethylcarbamoyl)ergoline-8-carboxamide; (8-beta)-(2-propenyl); n-(3-(dimethylamino)propyl)-n-((ethylamino)carbonyl)-6-ergoline-8-carboxamid; FCE-21336,Cabaser,Dostinex; (8b)-N-[3-(Dimethylamino)propyl]-N-[(ethylamino)carbonyl]-6-(2-propen-1-yl)- ergoline-8-carboxamide; Cabaser; Dostine; (8beta)-N-[3-(dimethylamino)propyl]-N-(ethylcarbamoyl)-6-(prop-2-en-1-yl)ergoline-8-carboxamide; (8β,10ξ)-N-[3-(dimethylamino)propyl]-N-(ethylcarbamoyl)-6-prop-2-en-1-ylergoline-8-carboxamide
  • 81409-90-7
  • C26H37N5O2
  • 451.6043
  • InChI=1/C26H37N5O2/c1-5-11-30-17-19(25(32)31(26(33)27-6-2)13-8-12-29(3)4)14-21-20-9-7-10-22-24(20)18(16-28-22)15-23(21)30/h5,7,9-10,16,19,21,23,28H,1,6,8,11-15,17H2,2-4H3,(H,27,33)/t19-,21?,23-/m1/s1
  • 卡麦角林 81409-90-7
  • 1.156g/cm3
  • 从乙醚得白色结晶,熔点102~104℃。急性毒性LD50小鼠(mg/kg):>400口服。

  • 长效多巴胺拮抗剂。用于治疗原发性或曲垂体瘤所引起的高催乳素症。