中文名称：马杜拉霉素
  • 克球皇; 马杜霉素铵; 马度米星铵盐; 马杜霉素铵盐; 马杜米星铵盐; 马杜拉霉素铵
  • Madubamycin ammonium
  • maduramicin ammonoium; princin ammonoum; Maduramicin; Maduramycine ammonium; 2-[(2R,3S,4S,5R,6S)-6-[(1R)-1-[(2S,5R,7S,8R,9S)-2-[(2R,5S)-5-[(2R,3S,5R)-3-[(2R,4S,5S,6S)-4,5-dimethoxy-6-methyl-tetrahydropyran-2-yl]oxy-5-[(2S,3S,5R,6S)-6-hydroxy-3,5,6-trimethyl-tetrahydropyran-2-yl]tetrahydrofuran-2-yl]-5-methyl-tetrahydrofuran-2-yl]-9-hydroxy-2,8-dimethyl-1,6-dioxaspiro[4.5]decan-7-yl]ethyl]-2-hydroxy-4,5-dimethoxy-3-methyl-tetrahydropyran-2-yl]acetamide hydrate; (2R,3S,4S,5R,6S)-6-[(1R)-1-[(2S,5R,7S,8R,9S)-2-[(2S,2'R,3'S,5R,5'R)-3'-[(2,6-Dideoxy-3,4-di-O-methyl-b-L-arabino-hexopyranosyl)oxy]octahydro-2-methyl-5'-[(2S,3S,5R,6S)-tetrahydro-6-hydroxy-3,5,6-trimethyl-2H-pyran-2-yl][2,2'-bifuran]-5-yl]-9-hydroxy-2,8-dimethyl-1,6-dioxaspiro[4.5]dec-7-yl]ethyl]tetrahydro-2-hydroxy-4,5-dimethoxy-3-methyl-2H-pyran-2-acetic acid monoammonium salt; Maduramycin Ammonium
  • 84878-61-5
  • C47H83NO17
  • 934.1584
  • InChI=1/C47H81NO16.H2O/c1-23-18-24(2)45(9,51)61-36(23)31-19-32(58-35-20-30(53-10)40(55-12)28(6)57-35)42(59-31)44(8)15-14-33(60-44)43(7)16-17-46(64-43)21-29(49)25(3)37(62-46)26(4)38-41(56-13)39(54-11)27(5)47(52,63-38)22-34(48)50;/h23-33,35-42,49,51-52H,14-22H2,1-13H3,(H2,48,50);1H2/t23-,24+,25+,26+,27-,28-,29-,30-,31+,32-,33+,35+,36-,37-,38-,39-,40-,41-,42+,43-,44-,45-,46+,47+;/m0./s1
  • 马杜拉霉素 84878-61-5
  • 964.7°C at 760 mmHg
  • 537.2°C
  • 0mmHg at 25°C
  • 熔点：165～167℃
    毒性LD50(mg/kg)：不具有致突变作用。根据14C标记化合物的放射性测定，以55E-6的剂量喂鸡7天以后，停药1天屠宰，对鸡体各组织测不出残留量。
    性状：白色结晶粉末
    溶解情况：不溶于水，可溶于大部分有机溶剂。
  • 用途：球虫杀灭剂，杀死宿主体内的寄生虫。美国FDA规定：仅用于肉鸡，每顿饲料添加4.54～5.54g（即5～6E-6）。本品优点是用量小，对马属动物无毒。
  •  T+:Very toxic;
  • R25:;
    R27:;
    R36:;
  • S26:;
    S28:;
    S36/37:;
    S45:;