| 英文品名 |
pegaptanib |
| 名称来源 |
p-INNList-87,2002;r-INNList-49,2003; |
| 别 名 |
EYE001; NX1838 |
| 化学表述 |
5'-ester of (2'-deoxy-2'-fluoro)C-Gm-Gm-A-A-(2'-deoxy-2'-fluoro)U-(2'-deoxy-2'-fluoro)C-Am-Gm-(2'-deoxy-2'-fluoro)U-Gm-Am-Am-(2'-deoxy-2'-fluoro)U-Gm-(2'-deoxy-2'-fluoro)C-(2'-deoxy-2'-fluoro)U-(2'-deoxy-2'-fluoro)U-Am-(2'-deoxy-2'-fluoro)U-Am-(2'-deoxy-2'-fluoro)C-Am-(2'-deoxy-2'-fluoro)U-(2'-deoxy-2'-fluoro)C-(2'-deoxy-2'-fluoro)C-Gm-(3'3')-dT with α,α'-[[(1S)-1-[[5-(phosphonooxy)pentyl]carbamoyl]pentane-1,5-diyl]bis(iminocarbonyl)]bis[ω-methoxypoly(oxyethane-1,2-diyl)] |
| CA登记号 |
222716-86-1 |
| 分 子 式 |
C294H370F13N107O188P28[C2H4O]n |
| 结 构 式 |
|
| 品种类别 |
抗肿瘤药>血管生成抑制药类>聚乙二醇化;angiogenesis inhibitor; |
| 简介 |
上市（Eyetech Pharmaceuticals, Inc.，美国）。Treatment of age-related macular degeneration disease (anti-VEGF apatamer) |
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