配方类型: |
DRUGS |
配方说明: |
Tablets (Phenobarbitone, 50 mg) |
配方组成: |
Dicalcium Phosphate Dihydrate/- Magnesium Stearate/0.5 Tablet Wt./200 mg Phenobarbitone/25.0 Relative Wt. Standard Deviation/0.60% Ejection Force/250 N Lactose (extra fine crystalline)/49.3 Crushing Strength (Schleuniger)/7.9 kg Friability (Roche, 100 rotations)/0.4% Disintegrating Time (USP XIX)/20 s Disintegrating Time (without using discs)/21 s "Primojel"/2.5 Microcrystalline Cellulose/22.5 Prednisone (micronized)/- Colloidal Silica/0.2 |
配制方法: |
Prepare by direct compression using an instrumented single punch tableting machine at a compression force of 20 kN. Tablet diameter: 7 mm for the prednisone tablets and 9 mm for the phenobarbitone tablets. After storage of the tablets at extreme humid conditions, 8 weeks 20 C and 85% relative humidity, the disintegration time was 20 s for the prednisone tablets and 29 s for the phenobarbitone tablets. |
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