英文品名 |
alvimopan |
名称来源 |
p-INNList-87,2002;r-INNList-49,2003; |
别 名 |
ADL 8-2698; LY246736 |
化学表述 |
[[(2S)-2-[[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]methyl]-3-phenylpropanoyl]amino]acetic acid |
CA登记号 |
156053-89-3 |
分 子 式 |
C25H32N2O4 |
结 构 式 |
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品种类别 |
术后肠梗阻用药>μ-阿片外周受体拮抗药类; μ-opioid receptor antagonist; |
简介 |
上市(Adolor Corporation,美国)。Treatment of opioid-induced bowel dysfunction, opioid-induced nausea and vomiting, postoperative ileus, idiopathic constipation, and irritable bowel syndrome (peripherally restricted mu opioid receptor antagonist) |
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