| 化学表述 |
immunoglobulin single chain VH-VH'-VH, trivalent bispecific anti-[Homo sapiens TNF (tumor necrosis factor, TNF superfamily member 2, TNFSF2, TNFA, TNF-alpha)] VH and anti-[Homo sapiens ALB (albumin, human serum albumin, HSA)] VH', humanized Lama glama monoclonal antibody;scVH-VH'-VH (1-363) [humanized VH (Homo sapiens IGHV3-74*01 (88.80%) -(IGHD)-IGHJ1*01 W118>R (105)) [8.8.8] (1-115) - 9-mer linker (tetraglycyl-seryl-triglycyl-seryl) (116-124) -humanized VH' (Homo sapiens IGHV3-23*04 (89.60%) -(IGHD)-IGHJ1*01 W118>S (229), G119>S (230) [8.8.8] (125-239) -9-mer linker (tetraglycylseryl- triglycyl-seryl) (240-248) -humanized VH (Homo sapiens IGHV3-74*01 (88.80%) -(IGHD)-IGHJ1*01 W118>R (353)(249-363) |
